B.S.Shylaja obtained Ph D from the Indian Institute of Astrophysics specializing in binaries among the hottest stars called Wolf-Rayet stars. Other subjects of her studies include novae, peculiar A stars, dwarf novae and comets. Over 60 research papers on these topics have been published in various national and international journals. She has presented papers in scientific conferences in Germany, Italy, Indonesia and South Africa.
Presently, after her tenure as the Director, she is associated with Bangalore Association for Science Education and is engaged in the activities of the Jawaharlal Nehru Planetarium and the associated Science Center. She is continuing research and is engaged in teaching astronomy and astrophysics to undergraduate and post-graduate students. Her activities include popularisation programmes, sky watch programmes, teachers' workshops and orientation programmes. She has written several articles on astronomical events both in English and in Kannada . She has given programmes on All India Radio, Gyanvani and Dooradarshan. She has authored / coauthored 17 books which include 5 in English.